Let $(M_{t}^{1})_{t\ge 0},\dots,(M_{t}^{m})_{t\ge 0}$ be continuous local martingales. Let $(V_{t}^{1})_{t\ge 0},\dots,(V_{t}^{n})_{t\ge 0}$ be continuous adapted processes of Variation, let $$Z_{t}=(M_{t}^{1},\dots,M_{t}^{m},V_{t}^{1},\dots,V_{t}^{n})\quad\forall t\ge 0$$Let $f:\mathbb{R}^{m}\times \mathbb{R}^{n}\to \mathbb{R}$ be $C^{0}$ s.t. $\frac{ \partial f }{ \partial x^{i} },\frac{ \partial ^{2}f }{ \partial x^{i}x^{j} },1\le i,\le m$, $\frac{ \partial f }{ \partial y^{k} },1\le k\le n$ exist and are $C^{0}$. Then, a.s. $\forall t\ge 0$ $$f(Z_{t})-f(Z_{0})=\sum_{i=1}^{m}\int\limits \mathbb{1}_{[0,t]}\frac{ \partial f }{ \partial x^{i} } (Z) \, dM^{i}+\sum_{k=1}^{n}\int\limits _{[0,t]}\frac{ \partial f }{ \partial y^{k} } (Z_{s}) \, dV_{s}+ \frac{1}{2}\sum_{i=1}^{m}\sum_{j=1}^{m}\int\limits _{[0,t]}\frac{ \partial ^{2}f }{ \partial x^{i}x^{j} } (Z_{s}) \, d[M^{i},M^{j}]_{s}$$